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ProgramNovember 23th (Chair: Daniel Jost, ENS de Lyon) 3-4 pm: Introduction Keynote speaker: Marcelo Nollmann (CBS, Montpellier, France) Visualizing chromosome organization and transcription in single cells 4-4:40 pm: Vera Pancaldi (CRCT, Toulouse, France) Network approaches to study chromatin interaction networks: from transcription to replication and beyond 4:40-4:45 pm: Break 4:45-5:00 pm: Short-talk: Peter Meister (Univ Bern, Switzerland) Folding of the nematode genome by SMC complexes 5:00-5:15 pm: Short-talk: Maxime Tortora (LBMC, ENS de Lyon, France) Liquid-liquid phase separation in nucleo: Insights from simple biophysical models 5:15-6 pm: John Marko (Northwestern Univ, USA) Loop extrusion, chromatin crosslinking, epigenetics, and the geometry, topology and mechanics of chromosomes and nuclei Conclusion Day 1
3-3:40 pm: Juanma Vaquerizas (MPI Molecular Biomedecine, Muenster, Germany) Chromatin Conformation in Development and Disease 3:40-4:20 pm: Dariusz Plewczynski (Univ Varsovia, Poland) Nuclear phase condensation model with the single chromatin loop resolution 4:20-4:30 pm: Break 4:30-4:45 pm: Short talk: Martin Holub (TU Delft, Netherlands) Genome-in-a-box: Unraveling the spatio-temporal DNA organization from the bottom-up 4:45-5:00 pm: Short talk: Shu Zhang (Univ Goettingen, Germany) The role of RNAPll in genome reorganization after mitosis and it links to loop extrusion 5:00-5:15 pm: Short talk: Amanda Camara (IPK, Gatersleben, Germany) How to walk the line? Simulating a pathway for the condensation of centromeric units in holocentric species 5:15-6 pm : Luca Giorgetti (FMI, Switzerland) Towards a quantitative understanding of long-range transcriptional regulation Conclusion Day 2
3-3:40 pm: Julien Mozziconacci (MNHN, Paris, France) The 3D genome shapes the regulatory code of developmental genes 3:40-4:20 pm: Angelo Rosa (SISSA, Trieste, Italy) Chromosome organization in interphase: Lessons from (ring) polymer physics 4:20-4:30 pm: Break 4:30-4:45 pm: Short talk: Nadège Guiglielmoni (Univ Libre Bruxelles, Belgium) Hic2gfa: phasing assembly graphs with chromosome conformation capture 4:45-5:00 pm: Short talk: Cristiano Petrini (IFOM, Milan, Italy) SAMMY-seq: a versatile method to study chromatin architecture 5:00-5:15 pm: Short talk: Polina Belokopytova (NSU, Russia) 3DPredictor: an algorithm for predicting spatial chromatin interactions 5:15-6 pm: Melike Lakadamyali (Univ Pennsylvania, USA) Visualizing chromatin organization and dynamics at high resolution Conclusion Day 3
3-3:40 pm: Ralf Everaers (LPENSL, ENS de Lyon, France) Understanding the large scale 4D Structure of the Drosophila Genome during Interphase in the course of Development 3:40-4:20 pm: Noam Kaplan (Technion Univ, Israel) Understanding 3D genome organization with explicit probabilistic models 4:20-4:30 pm: Break 4:30-4:45 pm: Short talk: Dusan Racko (Slovak Acad Sci, Slovakia) Entropic competition between supercoiled and torsionally relaxed chromatin fibres drives loop extrusion through pseudo-topologically bound cohesin at low levels of supercoiling 4:45-5:00 pm: Short talk: Maji Ajoy (IIT Bombay, India) The accidental ally: Nucleosomal barriers can accelerate cohesin mediated loop formation in chromatin 5:00-5:15 pm: Short talk: Anna Anchimiuk (Univ Lausanne, Switzerland) Does chromosome folding require SMCs to bypass each other? 5:15-6 pm: Kerstin Bystricky (LBME, Toulouse, France) Real-time imaging approaches to decipher transcription modulated chromatin dynamics Wrap-up |
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